LONGEVITY PROJECTS

Every road that could help extend your life.

See what can be reached now, what may accept participants and what could become useful later. Each project shows what it may mean for you and what has to happen next.

133 routes in the RejuvAccess record
Available nowAgelessRx

AgelessRx rapamycin research programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Available nowOrganOx

OrganOx liver perfusion platform

This could keep someone alive and healthier when an organ is failing by repairing it, supporting it or replacing it.

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Available nowTransMedics

TransMedics Organ Care System

This could keep someone alive and healthier when an organ is failing by repairing it, supporting it or replacing it.

See what this could mean for you
Late human studyUT Health San Antonio / ARPA-H PROSPR

ARPA-H VITAL-H healthspan drug trial

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Human studyLyGenesis

LyGenesis ectopic liver regeneration

This could keep someone alive and healthier when an organ is failing by repairing it, supporting it or replacing it.

See what this could mean for you
Human studyTransposon Therapeutics

Transposon TPN-101 LINE-1 programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Human studyUnited Therapeutics / Miromatrix

United Therapeutics miroliverELAP liver support

This could keep someone alive and healthier when an organ is failing by repairing it, supporting it or replacing it.

See what this could mean for you
Early human studyBioAge Labs

BioAge BGE-102 metabolic-ageing programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Early human studyBiVACOR

BiVACOR total artificial heart

This could keep someone alive and healthier when an organ is failing by repairing it, supporting it or replacing it.

See what this could mean for you
Early human studyCellvie

Cellvie therapeutic mitochondria

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Early human studyeGenesis

eGenesis EGEN-2784 xenokidney

This could keep someone alive and healthier when an organ is failing by repairing it, supporting it or replacing it.

See what this could mean for you
Early human studyJunevity

Junevity transcription-factor medicines

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Early human studyLife Biosciences

Life Biosciences ER-100 optic-nerve programme

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

See what this could mean for you
Early human studyLIfT BioSciences

LIfT BioSciences neutrophil therapy

This could help an older immune system respond better to infections, vaccines and damaged cells.

See what this could mean for you
Early human studyBoston University

New England Centenarian Study

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

See what this could mean for you
Early human studyNewLimit

NewLimit epigenetic reprogramming

If it works, this approach could restore healthier behaviour in ageing cells or repair biological damage that the body no longer fixes well on its own.

See what this could mean for you
Early human studyNYU Langone Health

NYU Langone xenotransplant research

This could keep someone alive and healthier when an organ is failing by repairing it, supporting it or replacing it.

See what this could mean for you
Early human studyAgelessRx and academic collaborators

PEARL rapamycin longevity study

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Early human studyRubedo Life Sciences

Rubedo RLS-1496 senescent-cell programme

If it works, it could remove or quiet damaged cells that build up with age and disturb the healthy cells around them.

See what this could mean for you
Early human studyUnited Therapeutics and Revivicor

United Therapeutics xenokidney programme

This could keep someone alive and healthier when an organ is failing by repairing it, supporting it or replacing it.

See what this could mean for you
Early human studyVandria

Vandria mitophagy medicines

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Human research and measurementUK Biobank

UK Biobank ageing research platform

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

See what this could mean for you
Laboratory or animal researchAltos Labs

Altos Labs cellular rejuvenation programme

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

See what this could mean for you
Laboratory or animal researchAmplifier Therapeutics

Amplifier autophagy medicines

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Laboratory or animal researchArda Therapeutics

Arda pathogenic-cell depletion platform

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Laboratory or animal researchCasma Therapeutics

Casma autophagy therapies

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Laboratory or animal researchCentaura

Centaura multi-pathway longevity programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Laboratory or animal researchCleara Biotech

Cleara anti-senescence programme

If it works, it could remove or quiet damaged cells that build up with age and disturb the healthy cells around them.

See what this could mean for you
Laboratory or animal researchCyclarity Therapeutics

Cyclarity 7-ketocholesterol removal

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Laboratory or animal researchDeciduous Therapeutics

Deciduous immune-senolytic programme

If it works, it could remove or quiet damaged cells that build up with age and disturb the healthy cells around them.

See what this could mean for you
Laboratory or animal researchElastrin Therapeutics

Elastrin vascular-elastin repair

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Laboratory or animal researchElevian

Elevian regenerative-factor programme

This research tests whether changing factors carried in blood can improve repair, inflammation or organ function.

See what this could mean for you
Laboratory or animal researchEpiterna

Epiterna small-molecule longevity programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Laboratory or animal researchFauna Bio

Fauna Bio hibernation-inspired medicines

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Laboratory or animal researchGenflow Biosciences

Genflow SIRT6 gene-therapy programme

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Laboratory or animal researchGerostate Alpha

Gerostate Alpha drug-repurposing platform

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Laboratory or animal researchGordian Biotechnology

Gordian in-vivo discovery platform

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Laboratory or animal researchIsterian Biotech

Isterian fibrosis-repair programme

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

See what this could mean for you
Laboratory or animal researchLento Bio

Lento Bio LB-01 lens-repair eyedrop programme

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

See what this could mean for you
Laboratory or animal researchLEV Foundation

LEV Foundation robust mouse rejuvenation

This work helps identify interventions worth taking into human studies and shows where promising ideas fail before people are exposed to them.

See what this could mean for you
Laboratory or animal researchLinkGevity

LinkGevity anti-necrotic programme

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Laboratory or animal researchMatter Bio

Matter Bio genome-integrity platform

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

See what this could mean for you
Laboratory or animal researchMitrix Bio

Mitrix mitochondrial transplantation

This could help cells make energy and remove worn-out components more effectively as the body ages.

See what this could mean for you
Laboratory or animal researchMogling Bio

Mogling stem-cell rejuvenation programme

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

See what this could mean for you
Laboratory or animal researchNapa Therapeutics

Napa NAD-metabolism programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Laboratory or animal researchNeuroAge Therapeutics

NeuroAge brain-resilience programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Laboratory or animal researchUS National Institute on Aging

NIA Interventions Testing Program

This work helps identify interventions worth taking into human studies and shows where promising ideas fail before people are exposed to them.

See what this could mean for you
Laboratory or animal researchOisín Biotechnologies

Oisin senolytic gene-therapy platform

If it works, it could remove or quiet damaged cells that build up with age and disturb the healthy cells around them.

See what this could mean for you
Laboratory or animal researchRefoxy Pharmaceuticals

Refoxy FOXO3 longevity medicines

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Laboratory or animal researchRejuvenate Bio

Rejuvenate Bio systemic gene-therapy platform

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Laboratory or animal researchRepair Biotechnologies

Repair Biotechnologies cholesterol-degrading platform

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

See what this could mean for you
Laboratory or animal researchRetro Biosciences

Retro Biosciences cellular reprogramming

If it works, this approach could restore healthier behaviour in ageing cells or repair biological damage that the body no longer fixes well on its own.

See what this could mean for you
Laboratory or animal researchRevel Pharmaceuticals

Revel AGE-crosslink breakers

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Laboratory or animal researchSamsara Therapeutics

Samsara autophagy platform

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Laboratory or animal researchShift Bioscience

Shift Bioscience virtual-cell rejuvenation programme

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Laboratory or animal researchSIWA Therapeutics

SIWA senescent-cell antibody programme

If it works, it could remove or quiet damaged cells that build up with age and disturb the healthy cells around them.

See what this could mean for you
Laboratory or animal researchUCSF and Vanderbilt University

The Kidney Project implantable bioartificial kidney

This could keep someone alive and healthier when an organ is failing by repairing it, supporting it or replacing it.

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Laboratory or animal researchTornado Therapeutics

Tornado selective mTOR programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Laboratory or animal researchTurn Biotechnologies

Turn Biotechnologies ERA platform

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Laboratory or animal researchUnited Therapeutics / Thymmune Therapeutics

United Therapeutics / Thymmune THY-100 thymus-cell programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Laboratory or animal researchVincere Biosciences

Vincere mitophagy programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Laboratory or animal researchYouthBio Therapeutics

YouthBio partial reprogramming programme

If it works, this approach could restore healthier behaviour in ageing cells or repair biological damage that the body no longer fixes well on its own.

See what this could mean for you
Early researchAlcor Life Extension Foundation

Alcor cryonics programme

The aim is to preserve a person or brain long enough for future technology to repair damage that cannot be treated today. It remains highly uncertain.

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Early researchUS National Institutes of Health

All of Us ageing research platform

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Early researchColumbia University Mailman School of Public Health / ARPA-H PROSPR

ARPA-H FAST ageing biomarkers

This will not extend life by itself, but it could help show which risks matter and whether an intervention is changing the body in a useful direction.

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Early researchLinnaeus Therapeutics / ARPA-H PROSPR

ARPA-H GPER healthspan programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Early researchNula Therapeutics / ARPA-H PROSPR

ARPA-H multi-system rejuvenation programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Early researchCambrian BioPharma / ARPA-H PROSPR

ARPA-H PrevenTOR mTORC1 programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Early researchAdvanced Research Projects Agency for Health

ARPA-H PROSPR

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Early researchUniversity of Rochester / ARPA-H PROSPR

ARPA-H reverse-transcriptase ageing programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Early researchStanford University / ARPA-H PROSPR

ARPA-H THRIVE healthspan score

This can improve health and reduce avoidable risk now, without waiting for a future treatment.

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Early researchBiomarkers of Aging Consortium

Biomarkers of Aging Consortium

This will not extend life by itself, but it could help show which risks matter and whether an intervention is changing the body in a useful direction.

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Early researchBioViva

BioViva self-experiment gene-therapy programme

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Early researchBuck Institute for Research on Aging

Buck Institute geroscience programmes

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Early researchCalico Life Sciences

Calico ageing biology and drug discovery

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Early researchCambrian Biopharma

Cambrian longevity-medicine portfolio

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Early researchCARMAT SAS

CARMAT Aeson total artificial heart

This could keep someone alive and healthier when an organ is failing by repairing it, supporting it or replacing it.

See what this could mean for you
Early researchCirculate Health

Circulate therapeutic plasma exchange

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Early researchClock Foundation

Clock Foundation epigenetic-clock programme

If it works, this approach could restore healthier behaviour in ageing cells or repair biological damage that the body no longer fixes well on its own.

See what this could mean for you
Early researchclock.bio

clock.bio human-cell rejuvenation atlas

This will not extend life by itself, but it could help show which risks matter and whether an intervention is changing the body in a useful direction.

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Early researchUniversity of California, Berkeley

Conboy plasma-dilution research

This research tests whether changing factors carried in blood can improve repair, inflammation or organ function.

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Early researchCryonics Institute

Cryonics Institute preservation programme

The aim is to preserve a person or brain long enough for future technology to repair damage that cannot be treated today. It remains highly uncertain.

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Early researchUniversity of Washington and partners

Dog Aging Project

This work helps identify interventions worth taking into human studies and shows where promising ideas fail before people are exposed to them.

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Early researchDunedin Multidisciplinary Health and Development Study

DunedinPACE pace-of-ageing measure

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Early researchMighty Therapeutics (formerly Stealth BioTherapeutics)

Elamipretide mitochondrial medicine

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Early researchEpiBone

EpiBone lab-grown bone

This could keep someone alive and healthier when an organ is failing by repairing it, supporting it or replacing it.

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Early researchEuropean Biostasis Foundation

European Biostasis Foundation research

The aim is to preserve a person or brain long enough for future technology to repair damage that cannot be treated today. It remains highly uncertain.

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Early researchFountain Therapeutics

Fountain phenotypic ageing screen

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Early researchGero

Gero AI ageing-target discovery

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Early researchGlenn Foundation for Medical Research

Glenn Centers for Biology of Aging Research

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Early researchGlycanAge

GlycanAge immune-age measurement

This could help an older immune system respond better to infections, vaccines and damaged cells.

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Early researchNational University of Singapore and global partners

Healthy Longevity Catalyst Awards

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Early researchUS National Academy of Medicine and global partners

Healthy Longevity Global Grand Challenge

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Early researchHevolution Foundation

Hevolution healthy-lifespan programmes

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Early researchHuman Longevity, Inc.

Human Longevity multi-omics programme

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Early researchInsilico Medicine

Insilico Medicine ageing-target discovery

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Early researchJuvenescence

Juvenescence longevity portfolio

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Early researchMax Planck Institute for Biology of Ageing

Killifish ageing research

This work helps identify interventions worth taking into human studies and shows where promising ideas fail before people are exposed to them.

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Early researchAnimal Bioscience

Leap Years canine healthy-ageing study

This work helps identify interventions worth taking into human studies and shows where promising ideas fail before people are exposed to them.

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Early researchAlbert Einstein College of Medicine

Longevity Genes Project

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Early researchLoyal

Loyal LOY-001 large-dog longevity programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

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Early researchLoyal

Loyal LOY-002 senior-dog longevity programme

This work helps identify interventions worth taking into human studies and shows where promising ideas fail before people are exposed to them.

See what this could mean for you
Early researchLoyal

Loyal LOY-003 large-dog longevity programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Early researchMassachusetts General Hospital

Mass General pig-kidney transplant programme

This could keep someone alive and healthier when an organ is failing by repairing it, supporting it or replacing it.

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Early researchMax Planck Institute for Biology of Ageing

Max Planck biology-of-ageing programmes

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Early researchMayo Clinic

Mayo Clinic senolytic trials programme

If it works, it could remove or quiet damaged cells that build up with age and disturb the healthy cells around them.

See what this could mean for you
Early researchUS Department of Veterans Affairs

Million Veteran Program ageing research

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Early researchMinicircle

Minicircle follistatin gene-therapy programme

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Early researchNectome

Nectome whole-body and brain preservation programme

This could protect memory, movement or other brain functions that become vulnerable with age.

See what this could mean for you
Early researchUS National Institutes of Health

NIH Cellular Senescence Network

If it works, it could remove or quiet damaged cells that build up with age and disturb the healthy cells around them.

See what this could mean for you
Early researchNational University of Singapore

NUS Centre for Healthy Longevity

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Early researchOneSkin

OneSkin OS-01 skin-ageing programme

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Early researchOptispan

Optispan preventive-longevity model

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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Early researchInternational primate-research collaboration

Primate Aging Database

This work helps identify interventions worth taking into human studies and shows where promising ideas fail before people are exposed to them.

See what this could mean for you
Early researchRejuvenate Bio

Rejuvenate Bio canine longevity studies

This work helps identify interventions worth taking into human studies and shows where promising ideas fail before people are exposed to them.

See what this could mean for you
Early researchRetro Biosciences

Retro Biosciences autophagy programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Early researchRetro Biosciences

Retro Biosciences plasma programme

This research tests whether changing factors carried in blood can improve repair, inflammation or organ function.

See what this could mean for you
Early researchSENS Research Foundation

SENS damage-repair research portfolio

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

See what this could mean for you
Early researchSouthern Cryonics

Southern Cryonics preservation programme

The aim is to preserve a person or brain long enough for future technology to repair damage that cannot be treated today. It remains highly uncertain.

See what this could mean for you
Early researchSouthwest National Primate Research Center

Southwest marmoset ageing programme

This work helps identify interventions worth taking into human studies and shows where promising ideas fail before people are exposed to them.

See what this could mean for you
Early researchAmerican Federation for Aging Research and partners

SuperAgers Family Study

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

See what this could mean for you
Early researchTally Health / Infinite Epigenetics

Tally Health biological-age programme

If it works, this approach could restore healthier behaviour in ageing cells or repair biological damage that the body no longer fixes well on its own.

See what this could mean for you
Early researchAmerican Federation for Aging Research

TAME metformin trial programme

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Early researchTomorrow Bio

Tomorrow Bio human biostasis

The aim is to preserve a person or brain long enough for future technology to repair damage that cannot be treated today. It remains highly uncertain.

See what this could mean for you
Early researchDog Aging Project

TRIAD rapamycin trial in dogs

If the effect in people is large enough, this could become a medicine used to slow one or more processes that drive age-related decline.

See what this could mean for you
Early researchIntervene Immune

TRIIM-X thymus-regeneration programme

This could help an older immune system respond better to infections, vaccines and damaged cells.

See what this could mean for you
Early researchTruDiagnostic

TruDiagnostic multi-omics ageing clocks

This will not extend life by itself, but it could help show which risks matter and whether an intervention is changing the body in a useful direction.

See what this could mean for you
Early researchUnited Therapeutics / Miromatrix

United Therapeutics / Miromatrix whole-organ engineering

This could keep someone alive and healthier when an organ is failing by repairing it, supporting it or replacing it.

See what this could mean for you
Early researchUnited Therapeutics

United Therapeutics organ manufacturing

This could keep someone alive and healthier when an organ is failing by repairing it, supporting it or replacing it.

See what this could mean for you
Early researchVaika Foundation

Vaika canine longevity programme

This work helps identify interventions worth taking into human studies and shows where promising ideas fail before people are exposed to them.

See what this could mean for you
Early researchVitaDAO

VitaDAO longevity research funding

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

See what this could mean for you
Early researchWake Forest Institute for Regenerative Medicine

Wake Forest regenerative-medicine programme

This could keep someone alive and healthier when an organ is failing by repairing it, supporting it or replacing it.

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Early researchXPRIZE Foundation

XPRIZE Healthspan

If the project succeeds, it could add another practical route to prevent, delay or repair age-related decline.

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